According to reports, Perry was found dead in a jacuzzi at his home, and no drugs were found at the scene.

Warner Brothers issued a statement on the death of Perry.

"We are devastated by the passing of our dear friend Matthew Perry. Matthew was an incredibly gifted actor and an indelible part of the Warner Bros. Television Group family. The impact of his comedic genius was felt around the world, and his legacy will live on in the hearts of so many. This is a heartbreaking day, and we send our love to his family, his loved ones, and all of his devoted fans," it said.

A spokesperson for the Los Angeles Police Department told PEOPLE that officers responded to a call at Perry's address regarding the death of a male in his 50s, but would not confirm the deceased's identity.

However, the police have ruled out any foul play.

Born in Williamstown, Massachusetts, Perry gained international recognition in the 1990s for playing Chandler Bing on the NBC television sitcom Friends (1994–2004) and earned a Screen Actors Guild Award for the role.

Perry starred in the television series Studio 60 on the Sunset Strip, and in films including Fools Rush In, Almost Heroes, The Whole Nine Yards, The Whole Ten Yards, The Ron Clark Story, and 17 Again.

In 2010, he provided the voice of Benny in the video game Fallout: New Vegas.

Perry was co-creator, co-writer, executive producer, and star of the ABC sitcom Mr. Sunshine, which ran from February to April 2011.

In August 2012, he starred as sportscaster Ryan King, on the NBC sitcom Go On. Perry later co-developed and starred in a revival of the CBS sitcom The Odd Couple portraying Oscar Madison from 2015 to 2017.

Canadian PM Justin Trudeau said he was shocked to learn about the death of the actor.

He posted on X: "Matthew Perry’s passing is shocking and saddening. I’ll never forget the schoolyard games we used to play, and I know people around the world are never going to forget the joy he brought them. Thanks for all the laughs, Matthew. You were loved – and you will be missed."

Actress Mellisa Jean said: "RIP Matthew Perry. I can't believe he's gone, but I just saw this video posted by someone outside his home. He was only 54.
#MatthewPerry #RIPMatthewPerry."

Paying her tribute to the Friends actor,  Mira Sornivo wrote: "Oh no!!! Matthew Perry!! You sweet, troubled soul!! May you find peace and happiness in Heaven, making everyone laugh with your singular wit!!!"

Warner Bros. TV, producer of the show 'Friends', posted: "We are devastated to learn of Matthew Perry’s passing. He was a true gift to us all. Our heart goes out to his family, loved ones, and all of his fans."

"Friends" actress Morgan Fairchild, remembered the co-star and wrote on X: "I’m heartbroken about the untimely death of my “son”, Matthew Perry. The loss of such a brilliant young actor is a shock. I’m sending love & condolences to his friends & family, especially his dad, John Bennett Perry, who I worked with on Flamingo Road & Falcon Crest. #RIPMatthew."